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    諾貝爾生理醫學獎獲得者邁克爾?畢曉普教授來訪我校

    文:張倬聞 郭曉蘭 冷政偉 圖:張倬聞 李欽軻 審核:楊竹秋 來源:黨委宣傳部 2017-09-19 23:15 點擊:

        9月19日上午,諾貝爾生理醫學獎獲得者邁克爾·畢曉普(J. Michael Bishop)教授來訪我校。成都高新區畢曉普癌癥研究所所長楊頓博士及其研究團隊一行陪同來訪。

        學校黨委書記張勇、院長杜勇熱情會見了來賓一行,并在高坪校區行政樓會議室進行了會面交流。黨委副書記、紀委書記朱燕萍,副院長雷軍、張小明,學院辦公室、科技處、外事辦等有關負責人陪同會見。

        當天下午,我校與成都高新區畢曉普癌癥研究所合作框架協議簽約儀式在順慶校區世紀會堂成功舉行。邁克爾·畢曉普教授、成都高新區畢曉普癌癥研究所所長楊頓,南充市人民政府副市長李在偉、市科技局副局長楊明,我校黨委書記張勇、院長杜勇,黨委副書記、紀委書記朱燕萍,副院長雷軍出席簽約儀式。畢曉普癌癥研究所科研團隊、我校各科研院所、各教學院系師生代表一千余人參加并見證此次簽約儀式。副院長張小明主持簽約儀式。

        成都高新區畢曉普癌癥研究所是世界范圍內唯一使用諾貝爾獎得者邁克爾·畢曉普教授名字命名的研究所,匯集了歐美在癌癥及相關領域的頂尖級人才組成學術委員會,具有較強的國際影響力。為進一步建設以天然產物提取物為基礎的新型篩選平臺,在癌癥基礎研究方面取得新的突破,開發出下一代精準抗癌小分子藥物,研究所擬依托我校在醫療領域的臨床資源和人才儲備優勢,開展長期、全面的產學研用合作,共同致力于抗癌新藥研發及臨床應用。

        隨后,畢曉普教授為我校師生帶來了題為“The Path to Cancer Genes:An Anatomy of Discovery”的精彩學術演講。

        1911年,在美國東海岸的一座農場里,一只母雞長了腫瘤,這看似是件常見的小事。然而,圍繞這個腫瘤,科學家們在半個多世紀里不斷探索,一步步揭開了癌癥此前從未被人所知的許多秘密--由此取得的一系列發現,使5位科學家先后3次登上了諾貝爾獎的領獎臺。這5位科學家之一,就是現年81歲的邁克爾·畢曉普教授。他向師生們講述了這段激動人心的科學探索之旅。

        畢曉普和瓦爾繆斯創立了癌基因理論,它告訴人們,細胞癌變的根本原因既不是病毒,也不是其他的致癌因素,而是存在于細胞自身的基因中。當受到物理、化學、病毒等因素的刺激后,原癌基因被激活,就會成為致癌基因。

        畢曉普在演講中介紹了他從最開始觀察性研究不斷深入到分子水平、基因水平的研究歷程,包括與冷泉港實驗室的科學家一起合作的研究經歷。并對病毒、染色體錯配、染色體突變等在腫瘤發生中的作用及機制作了詳細闡述。同時展望了“Cancer Genomics”在諸多方面的潛能,如:早期檢測、評估腫瘤風險、靶向治療等。他認為,前瞻性的眼光,冒險精神,科學精神,創新堅持是“Discovery”必備的品德。

        世紀會堂內座無虛席,氣氛熱烈,不少師生站著聆聽完整場演講。演講結束后,我校轉化醫學中心所長郭曉蘭教授、附屬醫院普外科冷政偉副教授分別就表觀遺傳學對DNA產物表達的修飾、表觀遺傳學在腫瘤治療中的地位與畢曉普教授進行了現場交流探討。面對我校研究生、本科生和留學生提出的問題,畢曉普教授耐心細致地一一解答,并對同學們及年輕科學家們寄予了厚望。

        訪問期間,畢曉普教授還曾接受我校大學生通訊社記者的采訪。當被問到對同學們有什么樣的建議和寄語時,他說道:“我覺得最重要的是去做自己想做的事,如果你想當科學家,那就去成為一名科學家,如果你想成為英文學者,那就去當英文學者。重要的是你要成為自己想成為的人,而非成為別人要你成為的人”。

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